{"id":4502,"date":"2023-06-01T11:30:28","date_gmt":"2023-06-01T11:30:28","guid":{"rendered":"https:\/\/regensight.com\/pre-clinical-validation-outcomes-of-theranostic-guided-corneal-cross-linking-published\/"},"modified":"2023-06-01T11:30:28","modified_gmt":"2023-06-01T11:30:28","slug":"pre-clinical-validation-outcomes-of-theranostic-guided-corneal-cross-linking-published","status":"publish","type":"post","link":"https:\/\/regensight.com\/en\/pre-clinical-validation-outcomes-of-theranostic-guided-corneal-cross-linking-publishe\/","title":{"rendered":"Pre-clinical validation outcomes of theranostic-guided corneal cross-linking published"},"content":{"rendered":"<p>In a recent study published in the prestigious <a href=\"https:\/\/journals.lww.com\/jcrs\/Fulltext\/2023\/06000\/Predicting_corneal_cross_linking_treatment.16.aspx\" target=\"_blank\" rel=\"noopener\">Journal of Cataract &amp; Refractive Surgery<\/a>, theranostic-guided corneal cross-linking has been confirmed to induce precise and predictive corneal tissue strengthening in eye-bank human donor tissues through\u00a0 real-time measurement of the riboflavin corneal concentration during treatment.<\/p>\n<p>The C4V CHROMO4VIS theranostic UV-A device used controlled UV-A light irradiation to induce both imaging and treatment of the cornea, providing a real-time measure of corneal riboflavin concentration and treatment efficacy (i.e., the theranostic score). The theranostic score showed high accuracy (94%) and precision (94%) to predict correctly samples that had improved tissue biomechanical strengthening (measured by air-puff dynamic tonometry), regardless of treatment protocol, i.e. with or without the corneal epithelium intact.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>In a recent study published in the prestigious Journal of Cataract &amp; Refractive Surgery, theranostic-guided corneal cross-linking has been confirmed to induce precise and predictive corneal tissue strengthening in eye-bank human donor tissues through\u00a0 real-time measurement of the riboflavin corneal concentration during treatment. The C4V CHROMO4VIS theranostic UV-A device used controlled UV-A light irradiation to [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":4500,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":""},"categories":[35],"tags":[43,45,44],"_links":{"self":[{"href":"https:\/\/regensight.com\/en\/wp-json\/wp\/v2\/posts\/4502"}],"collection":[{"href":"https:\/\/regensight.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/regensight.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/regensight.com\/en\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/regensight.com\/en\/wp-json\/wp\/v2\/comments?post=4502"}],"version-history":[{"count":0,"href":"https:\/\/regensight.com\/en\/wp-json\/wp\/v2\/posts\/4502\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/regensight.com\/en\/wp-json\/wp\/v2\/media\/4500"}],"wp:attachment":[{"href":"https:\/\/regensight.com\/en\/wp-json\/wp\/v2\/media?parent=4502"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/regensight.com\/en\/wp-json\/wp\/v2\/categories?post=4502"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/regensight.com\/en\/wp-json\/wp\/v2\/tags?post=4502"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}